Personalized triggered release of antimicrobials

The main objective of this project is to coat central venous catheters with a coating that can release antimicrobials on demand when an infection of the catheter occurs. This would potentially avert the need to change the catheter, and decrease costs, risk of thrombosis, and risk of short and long term vessel damage.

The results expected for this project include:

  1. Build a safety file to achieve workflow/product MDR compliance
  2. Produce an optimized design of the coated catherers
  3. Ex-vivo optimization and testing in an organ on a perfusion system before clinical implementation

The main objective of this project is to coat central venous catheters with a coating that can release antimicrobials on demand when an infection of the catheter occurs.

Project coördinator

Dr. Patrick van Rijn
Associate Professor, Biomedical Engineering, Universitair Medisch Centrum Groningen

Partners:

BioMedical Engineering group of the UMCG, Radiology dept of UMCG, Bether Encapsulates BV, Polyvation