Personalized triggered release of antimicrobials

The main objective of this project is to coat central venous catheters with a coating that can release antimicrobials on demand when an infection of the catheter occurs. This would potentially avert the need to change the catheter, and decrease costs, risk of thrombosis, and risk of short and long term vessel damage.

The results expected for this project include:

  • Build a safety file to achieve workflow/product MDR compliance
  • Produce an optimized design of the coated catherers
  • Ex-vivo optimization and testing in an organ on a perfusion system before clinical implementation

 

The project is a collaboration between the Biomedical Engineering Department, the Radiology Department and companies Bether Encapsulates and Polyvation. To know about the partners, please visit the page Partners.


If you have any question about the project or you would like to connect, please contact us via implants@umcg.nl.

The Just Transition Fund provides essential support, advancing the green and sustainable development of the Drenthe, Groningen, and Fryslân Provinces, the Municipality of Emmen, and the Northern Labour Market regions. The fund is co-financed by the European Union and the Dutch Ministry of Economic Affairs and Climate Policy and is made available by the regional funding agency Samenwerkingsverband Noord-Nederland (SNN), with support from the Province and Municipality of Groningen.

Partners:

BioMedical Engineering group of the UMCG, Radiology dept of UMCG, Bether Encapsulates BV, Polyvation

Project coördinator

Dr. Patrick van Rijn
Associate Professor, Biomedical Engineering, Universitair Medisch Centrum Groningen